Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289465 | 1.00 | CYP4F2 (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR | |
| SCHEMBL30744962 | 0.89 | OPRK1 (0.38) | OPRK1NPSR1TSHRKDM4EGMNN | |
| SCHEMBL20944537 | 0.89 | OPRK1 (0.38) | OPRK1NPSR1TSHRKDM4EGMNN | |
| SCHEMBL22117014 | 0.85 | TSHR (0.36) | OPRK1NPSR1TSHRKDM4EGMNN | |
| SCHEMBL24369751 | 0.83 | OPRK1 (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR | |
| SCHEMBL30402328 | 0.83 | ALDH1A1 (0.40) | CYP4F2CYP4A11NPSR1TSHRKDM4E | |
| SCHEMBL29572125 | 0.83 | MAPT (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR | |
| SCHEMBL30849372 | 0.83 | KDM4E (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR | |
| SCHEMBL17544367 | 0.83 | ALDH1A1 (0.40) | CYP4F2CYP4A11NPSR1TSHRKDM4E | |
| SCHEMBL18668409 | 0.83 | MAPT (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118401514-A | 3, 4-Dihydroisoquinolin-1 (2H) -one derivatives as STING antagonists and uses thereof | 百济神州有限公司 | 2024-07-26 | — | — | CN | disclosed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |