Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 13/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745103 | 1.00 | CYP4F2 (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR | |
| SCHEMBL30744962 | 0.89 | OPRK1 (0.38) | OPRK1NPSR1TSHRKDM4EGMNN | |
| SCHEMBL20944537 | 0.89 | OPRK1 (0.38) | OPRK1NPSR1TSHRKDM4EGMNN | |
| SCHEMBL22117014 | 0.85 | TSHR (0.36) | OPRK1NPSR1TSHRKDM4EGMNN | |
| SCHEMBL24369751 | 0.83 | OPRK1 (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR | |
| SCHEMBL30402328 | 0.83 | ALDH1A1 (0.40) | CYP4F2CYP4A11NPSR1TSHRKDM4E | |
| SCHEMBL29572125 | 0.83 | MAPT (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR | |
| SCHEMBL30849372 | 0.83 | KDM4E (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR | |
| SCHEMBL17544367 | 0.83 | ALDH1A1 (0.40) | CYP4F2CYP4A11NPSR1TSHRKDM4E | |
| SCHEMBL18668409 | 0.83 | MAPT (0.40) | CYP4F2CYP4A11OPRK1NPSR1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260078119-A1 | DEGRADER COMPOUNDS AND USES THEREOF | BRISTOL MYERS SQUIBB CO (US) | 2026-03-19 | — | — | US | disclosed |
| EP-4688771-A1 | NOVEL FAK DEGRADER COMPOUNDS AND USES THEREOF | Bristol-Myers Squibb Company (US) | 2026-02-11 | — | — | EP | disclosed |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | NIDO BIOSCIENCES, INC. (US) | 2025-10-21 | — | — | US | disclosed |
| EP-3952870-B1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | NANJING ZENSHINE PHARMACEUTICALS CO LTD (CN) | 2025-09-24 | — | — | EP | disclosed |
| US-12351570-B2 | Disubstituted alkyne derivatives | MERCK PATENT GMBH (DE) | 2025-07-08 | — | — | US | disclosed |
| US-20250154107-A1 | 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof | BEIGENE SWITZERLAND GMBH (CH) | 2025-05-15 | — | — | US | disclosed |
| US-20250122176-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES INC (US) | 2025-04-17 | — | — | US | disclosed |
| US-20250092021-A9 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | NIDO BIOSCIENCES, INC. | 2025-03-20 | — | — | US | disclosed |
| US-20250034134-A1 | 15-PGDH INHIBITOR AND USE THEREOF | Wuhan Humanwell Innovative Drug Research and Development Center Limited Company (CN) | 2025-01-30 | — | — | US | disclosed |
| US-20240408088-A1 | PYRAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | ABBISKO THERAPEUTICS CO., LTD. (CN) | 2024-12-12 | — | — | US | disclosed |
| US-20110053953-A1 | AZA-Isoindolones and Their Use as Metabotropic Glutamate Receptor Potentiators - 613 | ASTRAZENECA AB (SE) | 2011-03-03 | — | — | US | disclosed |
| WO-2010128324-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010128324-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | WO | disclosed |
| US-20100286118-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | US | disclosed |
| US-20100286118-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | US | disclosed |
| US-20100286118-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | US | disclosed |
| WO-2010129620-A1 | IMIDAZO [ 1, 2 -A] PYRIDIN-2 -YL-PHENYL DERIVATIVES TO BE USED IN CANCER TREATMENT | ALLA CHEM, LLC (US) | 2010-11-11 | — | — | WO | disclosed |
| EP-2114940-A1 | AZA-ISOINDOLONES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS - 613 | AstraZeneca AB (SE) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008100715-A1 | AZA-ISOINDOLONES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS - 613 | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | WO | disclosed |
| WO-2008100715-A1 | AZA-ISOINDOLONES AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR POTENTIATORS - 613 | ASTRAZENECA AB (SE) | 2008-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100286118-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | CNR1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CNR2 | CYP4F2 190/4885CYP4A11 138/4885OPRK1 270/4885 |
| US-20240408088-A1 | PYRAZOLE DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | PRMT5, PRMT1, PRMT8 | CYP4F2 177/4885CYP4A11 120/4885OPRK1 4725/4885 |
| US-12351570-B2 | Disubstituted alkyne derivatives | BRCA1, MYC, PCNA | CYP4F2 2833/4885CYP4A11 1749/4885OPRK1 4124/4885 |
| US-20260078119-A1 | DEGRADER COMPOUNDS AND USES THEREOF | CTTN, SRC, PTK2 | CYP4F2 4149/4885CYP4A11 3075/4885OPRK1 567/4885 |
| US-20250122176-A1 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | CYP4F2 3531/4885CYP4A11 1496/4885OPRK1 125/4885 |
| US-20250034134-A1 | 15-PGDH INHIBITOR AND USE THEREOF | HPGD, UGDH, PGD | CYP4F2 135/4885CYP4A11 77/4885OPRK1 2213/4885 |
| US-20110053953-A1 | AZA-Isoindolones and Their Use as Metabotropic Glutamate Receptor Potentiators - 613 | GRIN3A, GRM3, GRIN1 | CYP4F2 1832/4885CYP4A11 914/4885OPRK1 332/4885 |
| US-20250092021-A9 | INDOLE COMPOUNDS AS ANDROGEN RECEPTOR MODULATORS | AR, FSHR, NR5A1 | CYP4F2 3531/4885CYP4A11 1496/4885OPRK1 125/4885 |
| US-12448368-B2 | Indole compounds as androgen receptor modulators | AR, FSHR, ADRB3 | CYP4F2 3721/4885CYP4A11 1703/4885OPRK1 145/4885 |
| US-20250154107-A1 | 3,4-Dihydroisoquinolin-1(2H)-Ones Derivatives as STING Antagonists and the Use Thereof | STING1, IRF3, MAVS | CYP4F2 4275/4885CYP4A11 3150/4885OPRK1 1842/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.