Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.49 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151112 | 1.00 | MGLL (0.50) | MGLLALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL10459035 | 0.80 | NPC1 (0.51) | MGLLALDH1A1RAB9AMAPTKMT2A | |
| SCHEMBL29151131 | 0.78 | CA12 (0.49) | MGLLALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL29488646 | 0.78 | CA12 (0.49) | MGLLALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18770625 | 0.77 | NPBWR1 (0.43) | ALDH1A1SMN1; SMN2MAPTNPBWR1MCHR1 | |
| SCHEMBL30745148 | 0.77 | CA12 (0.47) | MGLLALDH1A1KMT2ANPBWR1MEN1 | |
| SCHEMBL29151050 | 0.77 | CA12 (0.47) | MGLLALDH1A1KMT2ANPBWR1MEN1 | |
| SCHEMBL29488639 | 0.77 | CA12 (0.47) | MGLLALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL544605 | 0.75 | POLB (0.58) | MGLLALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL18770698 | 0.75 | RAB9A (0.60) | MGLLALDH1A1RAB9ASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510470-A | Pyridazinone compounds and application thereof | 暨南大学 | 2024-02-06 | — | — | CN | disclosed |