Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31598413 | 0.85 | TRPV3 (0.36) | TRPV3MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL30745407 | 0.82 | USP30 (0.38) | TRPV3GPR119USP30 | |
| SCHEMBL30745417 | 0.80 | MEN1 (0.39) | MEN1KMT2ANR1H2NR1H3USP30 | |
| SCHEMBL30745395 | 0.76 | MEN1 (0.35) | MEN1KMT2AGPR119USP30 | |
| SCHEMBL31598162 | 0.76 | IDH1 (0.42) | MEN1KMT2ANR1H2NR1H3 | |
| SCHEMBL29580612 | 0.75 | MEN1 (0.39) | MEN1KMT2AGPR119USP30ATM | |
| SCHEMBL31597791 | 0.74 | LMNA (0.35) | MEN1KMT2ANR1H2NR1H3GPR119 | |
| SCHEMBL31413096 | 0.73 | USP30 (0.46) | MEN1KMT2ANR1H2NR1H3GPR119 | |
| SCHEMBL31598218 | 0.73 | JAK1 (0.35) | MEN1KMT2ANR1H2NR1H3GPR119 | |
| SCHEMBL17747329 | 0.73 | TACR1 (0.41) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |