Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 3/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.32 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745353 | 0.85 | TRPV3 (0.44) | TRPV3NR1H2NR1H3GRM5MEN1 | |
| SCHEMBL31598282 | 0.81 | HDAC1 (0.33) | GRM5MEN1KMT2ALMNANPSR1 | |
| SCHEMBL31597791 | 0.79 | LMNA (0.35) | NR1H2NR1H3CYP3A4CYP1A2POLB | |
| SCHEMBL31598162 | 0.78 | IDH1 (0.42) | NR1H2NR1H3MEN1KMT2AMGLL | |
| SCHEMBL30745417 | 0.78 | MEN1 (0.39) | NR1H2NR1H3POLBGRM5MEN1 | |
| SCHEMBL29580612 | 0.78 | MEN1 (0.39) | POLBGRM5MEN1KMT2ALMNA | |
| SCHEMBL30745407 | 0.77 | USP30 (0.38) | TRPV3CYP3A4USP30GPR119CYP3A5 | |
| SCHEMBL31413096 | 0.75 | USP30 (0.46) | NR1H2NR1H3CYP3A4CYP2C19GRM5 | |
| SCHEMBL17747329 | 0.75 | TACR1 (0.41) | POLBMEN1KMT2ANPSR1 | |
| SCHEMBL17747380 | 0.74 | GPR119 (0.43) | CYP3A4CYP1A2POLBCYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655695-B | Substituted furopyrimidine compounds as PDE1 inhibitors | 达特神经科学有限公司 | 2025-05-27 | — | — | CN | disclosed |