Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 7/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.37 |
| ▸ | GRM5 | P41594 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740755 | 0.94 | LNPEP (0.38) | LNPEPJAK2JAK1GPR119 | |
| SCHEMBL29826311 | 0.84 | LNPEP (0.42) | LNPEPGPR119 | |
| SCHEMBL29825830 | 0.83 | GPR119 (0.54) | LNPEPGPR119 | |
| SCHEMBL29157077 | 0.81 | PIK3CD (0.48) | LNPEPGPR119 | |
| SCHEMBL30111143 | 0.81 | PIK3CD (0.48) | LNPEPGPR119 | |
| SCHEMBL24791730 | 0.81 | PIK3CD (0.48) | LNPEPGPR119 | |
| SCHEMBL30053592 | 0.81 | USP30 (0.43) | LNPEPJAK2JAK1GPR119 | |
| SCHEMBL24791774 | 0.81 | USP30 (0.43) | LNPEPJAK2JAK1GPR119 | |
| SCHEMBL30745409 | 0.81 | NR1H2 (0.40) | GPR119GRM5MEN1KMT2A | |
| SCHEMBL30740827 | 0.80 | GPR119 (0.38) | LNPEPGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |