Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745372 | 0.94 | LNPEP (0.39) | LNPEPJAK2JAK1GPR119 | |
| SCHEMBL30740827 | 0.86 | GPR119 (0.38) | LNPEPGPR119 | |
| SCHEMBL30740733 | 0.84 | ALDH1A1 (0.41) | OPRK1LMNANPSR1ALDH1A1 | |
| SCHEMBL30668743 | 0.82 | GPR119 (0.44) | GPR119 | |
| SCHEMBL29825830 | 0.82 | GPR119 (0.54) | LNPEPCHEK2GPR119 | |
| SCHEMBL30740835 | 0.81 | MAPT (0.42) | GPR119OPRK1NPSR1UCHL1 | |
| SCHEMBL29826311 | 0.80 | LNPEP (0.42) | LNPEPGPR119 | |
| SCHEMBL30740850 | 0.80 | CHEK2 (0.42) | CHEK2 | |
| SCHEMBL30745375 | 0.79 | ALDH1A1 (0.45) | LMNANPSR1UCHL1ALDH1A1 | |
| SCHEMBL24791730 | 0.78 | PIK3CD (0.48) | LNPEPGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |