Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 13/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 12/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745350 | 0.85 | NR1H2 (0.42) | NR1H2NR1H3RXRA | |
| SCHEMBL30745393 | 0.79 | MRGPRX4 (0.47) | — | |
| SCHEMBL22861508 | 0.78 | RORC (0.43) | NR1H2NR1H3HCRTR2RXRAGPR119 | |
| SCHEMBL17881905 | 0.78 | RORC (0.43) | NR1H2NR1H3HCRTR2RXRAGPR119 | |
| SCHEMBL11311051 | 0.78 | STS (0.49) | STSGPR119 | |
| SCHEMBL17747380 | 0.72 | GPR119 (0.43) | GPR119 | |
| SCHEMBL4041543 | 0.71 | HSD11B1 (0.33) | NR1H2NR1H3HCRTR2GPR119 | |
| SCHEMBL4041548 | 0.71 | HSD11B1 (0.33) | NR1H2NR1H3HCRTR2GPR119 | |
| SCHEMBL17747329 | 0.71 | TACR1 (0.41) | — | |
| SCHEMBL29514529 | 0.71 | GPR119 (0.39) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117545748-A | Benzimidazolyl GLP-1GPCR receptor agonists, pharmaceutical compositions comprising the same, and methods of use thereof | 卡莫特医疗有限公司 | 2024-02-09 | — | — | CN | disclosed |