Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.57 |
| ▸ | ACHE | P22303 | 2/20 | 0.52 |
| ▸ | BACE1 | P56817 | 2/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 3/20 | 0.51 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745470 | 0.90 | AR (0.58) | ARMAOBABCG2ACHEBACE1 | |
| SCHEMBL30745488 | 0.89 | ACHE (0.65) | MAOBACHEBACE1CXCL12 | |
| SCHEMBL30745476 | 0.88 | MAOB (0.61) | MAOB | |
| SCHEMBL25228491 | 0.84 | AR (0.70) | ARMAOBABCG2ACHEBACE1 | |
| SCHEMBL30745478 | 0.83 | MAOB (0.56) | ARMAOBABCG2CXCL12 | |
| SCHEMBL30745510 | 0.81 | ABCG2 (0.53) | ARMAOBABCG2ACHEBACE1 | |
| SCHEMBL30745495 | 0.80 | ACHE (0.54) | MAOBABCG2ACHEBACE1CXCL12 | |
| SCHEMBL30745511 | 0.79 | SMN1; SMN2 (0.53) | ARMAOBABCG2ACHEBACE1 | |
| SCHEMBL30745497 | 0.79 | MAOB (0.61) | MAOBACHEBACE1 | |
| SCHEMBL30745430 | 0.79 | ACHE (0.67) | ABCG2ACHEBACE1CXCL12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | disclosed |