Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 16/20 | 0.61 |
| ▸ | MAOA | P21397 | 13/20 | 0.61 |
| ▸ | APP | P05067 | 7/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745497 | 0.91 | MAOB (0.61) | MAOBMAOAAPPMEN1USP2 | |
| SCHEMBL30745488 | 0.88 | ACHE (0.65) | MAOBMAOAAPP | |
| SCHEMBL30745458 | 0.88 | AR (0.57) | MAOB | |
| SCHEMBL30745509 | 0.83 | MEN1 (0.56) | MAOBMAOAAPPMEN1USP2 | |
| SCHEMBL30745495 | 0.81 | ACHE (0.54) | MAOBMAOAMEN1MAPTMAPK1 | |
| SCHEMBL30745468 | 0.81 | MAOB (0.54) | MAOBMAOAMEN1USP2MAPT | |
| SCHEMBL30745430 | 0.81 | ACHE (0.67) | MEN1MAPTMAPK1KMT2AL3MBTL1 | |
| SCHEMBL30745470 | 0.81 | AR (0.58) | MAOBMEN1MAPTMAPK1KMT2A | |
| SCHEMBL30745466 | 0.80 | MAOA (0.53) | MAOBMAOAAPPMEN1USP2 | |
| SCHEMBL30745483 | 0.80 | MAOB (0.53) | MAOBMAOAMEN1USP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | disclosed |