Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745464 | 0.89 | CTSL (0.57) | MAOBMEN1LMNAMAPTKMT2A | |
| SCHEMBL30745438 | 0.89 | MAOB (0.58) | MAOBMEN1LMNAMAPTKMT2A | |
| SCHEMBL30745509 | 0.88 | MEN1 (0.56) | MAOBMEN1LMNAMAPTKMT2A | |
| SCHEMBL30745458 | 0.83 | AR (0.57) | MAOBABCG2ARCXCL12 | |
| SCHEMBL30745426 | 0.79 | MAPT (0.59) | MAOBMEN1LMNAMAPTKMT2A | |
| SCHEMBL30745498 | 0.78 | MAOB (0.53) | MAOBMEN1LMNAMAPTKMT2A | |
| SCHEMBL30745431 | 0.78 | MAPT (0.51) | MAOBMEN1LMNAMAPTKMT2A | |
| SCHEMBL30745507 | 0.78 | CTSL (0.59) | MAOBMEN1LMNAMAPTKMT2A | |
| SCHEMBL30745425 | 0.78 | MEN1 (0.60) | MAOBMEN1LMNAMAPTKMT2A | |
| SCHEMBL30745496 | 0.77 | MAOB (0.53) | MAOBMEN1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | claimed |
| CN-117567303-A | Chalcone Mannich base compound, pharmaceutical composition, preparation method and application thereof | 安徽中医药大学 | 2024-02-20 | — | — | CN | disclosed |