SCHEMBL30745574

SCHEMBL30745574

c1ccc2c(c1)Cc1c-2cccc1[Si](c1cccc2c1Cc1ccccc1-2)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.52
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
HTR7 P34969 1/20 0.41
HTR2B P41595 1/20 0.41
DRD2 P14416 1/20 0.40
DRD4 P21917 1/20 0.40
DRD3 P35462 1/20 0.40
MAOA P21397 1/20 0.40
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA6 P23280 1/20 0.39
KDR P35968 1/20 0.39
ADORA2A P29274 1/20 0.39
ADORA1 P30542 1/20 0.39
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
MAPT P10636 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30745575 1.00 PNMT (0.52) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL28970858 0.89 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL5980985 0.89 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL5982506 0.85 PNMT (0.41) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL29843943 0.84 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6671922 0.84 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL61027 0.84 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL5981385 0.84 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL2546781 0.84 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30103334 0.82 PNMT (0.63) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117567728-A Tetrafluorenyl silane-benzothiadiazole conjugated microporous polymer nanoparticle and preparation method thereof 长春理工大学 2024-02-20 CN claimed
CN-117567728-A Tetrafluorenyl silane-benzothiadiazole conjugated microporous polymer nanoparticle and preparation method thereof 长春理工大学 2024-02-20 CN disclosed
CN-117567728-A Tetrafluorenyl silane-benzothiadiazole conjugated microporous polymer nanoparticle and preparation method thereof 长春理工大学 2024-02-20 CN disclosed