SCHEMBL61027

SCHEMBL61027

C[Si](C)(c1cccc2c1Cc1ccccc1-2)c1cccc2c1Cc1ccccc1-2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.49
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
HTR7 P34969 1/20 0.40
HTR2B P41595 1/20 0.40
DRD2 P14416 1/20 0.38
DRD4 P21917 1/20 0.38
DRD3 P35462 1/20 0.38
PGR P06401 1/20 0.38
MAOA P21397 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
KDR P35968 1/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29843943 1.00 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL5981385 0.89 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6671922 0.89 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL31530502 0.85 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6672427 0.85 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL6063638 0.85 PNMT (0.50) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL8971825 0.85 PNMT (0.46) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30745574 0.84 PNMT (0.52) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL30745575 0.84 PNMT (0.52) PNMTNPC1RAB9AHTR7HTR2B
SCHEMBL8086440 0.84 PNMT (0.49) PNMTNPC1RAB9AHTR7HTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 288 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1249782-A None JP disclosed
US-12590174-B2 Curable compositions comprising telechelic polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-31 US disclosed
EP-3902810-B1 CURABLE COMPOSITIONS COMPRISING TELECHELIC POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3902808-B1 CURABLE COMPOSITIONS COMPRISING UNSATURATED POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2026-01-14 EP disclosed
EP-3356374-B1 MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2025-09-24 EP disclosed
EP-3902807-B1 ORGANOMETALLIC CHAIN TRANSFER AGENTS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-09 EP disclosed
US-12351707-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2025-07-08 US disclosed
US-12275810-B2 Telechelic polyolefins and processes for preparing the same DOW GLOBAL TECHNOLOGIES LLC (US) 2025-04-15 US disclosed
US-12180314-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2024-12-31 US disclosed
US-12129368-B2 Curable compositions comprising unsaturated polyolefins DOW GLOBAL TECHNOLOGIES LLC (US) 2024-10-29 US disclosed
US-5565533-A SLURRY POLYMERIZATION IN PRESENCE OF A METALLOCENE CATALYST MONTELL TECHNOLOGY COMPANY BV (NL) 1996-10-15 US disclosed
EP-0729968-A1 Bridged bis-fluorenyl metallocenes, process for the preparation thereof and use thereof in catalysts for the polymerization of olefins Montell Technology Company bv (NL) 1996-09-04 EP disclosed
EP-0729984-A1 Atactic copolymers of propylene with ethylene Montell Technology Company bv (NL) 1996-09-04 EP disclosed
EP-0647243-A1 PROCESS FOR PREPARING AN ETHYLENIC COPOLYMER Montell Technology Company bv (NL) 1995-04-12 EP disclosed
EP-0632066-A1 Elastomeric copolymers of ethylene with propylene and process for their preparation Montell Technology Company bv (NL) 1995-01-04 EP disclosed
EP-0624604-A1 Elastomeric copolymers of ethylene with alpha-olefins and process for their preparation Montell Technology Company bv (NL) 1994-11-17 EP disclosed
EP-0604908-A2 Metallocene compounds having ligands of fluorenylic type Montell Technology Company bv (NL) 1994-07-06 EP disclosed
CN-1087097-A The method for preparing ethylene copolymer SPHERILENE SRL (IT) 1994-05-25 CN disclosed
WO-1993025591-A1 PROCESS FOR PREPARING AN ETHYLENIC POLYMER SPHERILENE S.R.L. (IT) 1993-12-23 WO disclosed
JP-H01249782-A POTASSIUM SALT OF ORGANIC SILICON COMPOUND FOR CATALYST HAVING HIGH ACTIVITY AND PRODUCTION THEREOF MITSUBISHI METAL CORP 1989-10-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12129368-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 PNMT 3858/4885NPC1 1682/4885RAB9A 4806/4885
US-12590174-B2 Curable compositions comprising telechelic polyolefins CCT2, TCP1, ECH1 PNMT 1496/4885NPC1 3703/4885RAB9A 4811/4885
US-12351707-B2 Curable compositions comprising unsaturated polyolefins ACSL6, ELOVL6, ALOX5 PNMT 3858/4885NPC1 1682/4885RAB9A 4806/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.