SCHEMBL5980985

SCHEMBL5980985

c1ccc([Si](c2ccccc2)(c2cccc3c2Cc2ccccc2-3)c2cccc3c2Cc2ccccc2-3)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.46
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
KDR P35968 2/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
HTR7 P34969 1/20 0.38
HTR2B P41595 1/20 0.38
ACHE P22303 2/20 0.37
BCHE P06276 2/20 0.37
DRD2 P14416 1/20 0.37
DRD4 P21917 1/20 0.37
DRD3 P35462 1/20 0.37
PDGFRB P09619 1/20 0.36
MAOA P21397 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
KDM4E B2RXH2 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28970858 0.96 PNMT (0.46) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL30745575 0.89 PNMT (0.52) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL30745574 0.89 PNMT (0.52) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL5982517 0.83 PNMT (0.39) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL7638661 0.83 PNMT (0.44) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL6676042 0.83 PNMT (0.36) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL18017363 0.83 MAP3K9 (0.38) PNMTNPC1RAB9AACHEBCHE
SCHEMBL18593880 0.81 PNMT (0.42) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL6571789 0.80 PGR (0.39) PNMTNPC1RAB9AKDRADORA2A
SCHEMBL18593861 0.80 PNMT (0.41) PNMTNPC1RAB9AKDRADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7135242-B2 Electroluminescent polymer, bisfluorenylsilane compound and organic electroluminescent element SONY CORPORATION (JP) 2006-11-14 US disclosed
EP-1553119-A1 ELECTROLUMINESCENT POLYMERS, BISFLUORENYLSILANES, AND ORGANIC ELECTROLUMINESCENT DEVICES SONY CHEMICALS CORP. (JP) 2005-07-13 EP disclosed
US-20050079382-A1 Electroluminescent polymer bisfluorenylsilane compound and organic electroluminescent element SONY CORPORATION (JP) 2005-04-14 US disclosed
EP-0963990-B1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL CO (JP) 2004-10-06 EP disclosed
US-6197990-B1 REACTING CYCLOPENTADIENE AND METAL HYDRIDE IN PRESENCE OF AMINE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-03-06 US disclosed
EP-0963990-A1 PROCESS FOR PRODUCING CYCLOPENTADIENYL METAL SALTS AND PROCESS FOR PRODUCING CYCLOPENTADIENE DERIVATIVES BY UTILIZING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-12-15 EP disclosed
EP-0604908-A2 Metallocene compounds having ligands of fluorenylic type Montell Technology Company bv (NL) 1994-07-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050079382-A1 Electroluminescent polymer bisfluorenylsilane compound and organic electroluminescent element EEF1D, POLL, ELP1 PNMT 1107/4885NPC1 3353/4885RAB9A 296/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.