Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.45 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745881 | 0.86 | MAOB (0.45) | EPHX1MAOBSLC6A2SLC6A4PARP10 | |
| SCHEMBL30745863 | 0.86 | MAOB (0.45) | EPHX1MAOBSLC6A2SLC6A4PARP10 | |
| SCHEMBL324161 | 0.82 | PARP10 (0.59) | CA1CA2MAOBSLC6A2SLC6A4 | |
| SCHEMBL30745869 | 0.81 | EPHX2 (0.46) | MAOBEPHX2NR1H4HDAC3NCOR1 | |
| SCHEMBL30745888 | 0.81 | EPHX2 (0.46) | MAOBEPHX2NR1H4HDAC3NCOR1 | |
| SCHEMBL30745912 | 0.81 | RAB9A (0.42) | MAOBPARP10HDAC3NCOR1HDAC1 | |
| SCHEMBL30745882 | 0.81 | MAOB (0.57) | CA12CA1CA2CA9MAOB | |
| SCHEMBL13581190 | 0.81 | ALDH1A1 (0.56) | EPHX1CA12CA1CA2CA9 | |
| SCHEMBL5377066 | 0.81 | ALDH1A1 (0.56) | EPHX1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL11888844 | 0.80 | PARP10 (0.57) | CA1CA2MAOBSLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |