Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745888 | 1.00 | EPHX2 (0.46) | EPHX2NR1H4PTPRZ1PTPN1MEN1 | |
| SCHEMBL30745912 | 0.88 | RAB9A (0.42) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30745896 | 0.85 | HDAC1 (0.46) | EPHX2NR1H4PTPRZ1PTPN1MEN1 | |
| SCHEMBL2541283 | 0.85 | KIF11 (0.54) | EPHX2NR1H4PTPRZ1PTPN1KMT2A | |
| SCHEMBL30745882 | 0.85 | MAOB (0.57) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30745872 | 0.81 | EPHX1 (0.52) | EPHX2NR1H4MAOBHDAC3NCOR1 | |
| SCHEMBL27680079 | 0.79 | ALDH1A1 (0.68) | EPHX2NR1H4PTPRZ1PTPN1MEN1 | |
| SCHEMBL15196503 | 0.79 | PLA2G10 (0.59) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL8144109 | 0.79 | PLA2G10 (0.59) | MEN1KMT2ARAB9ANPC1SMN1; SMN2 | |
| SCHEMBL30745904 | 0.78 | PTPRZ1 (0.72) | PTPRZ1PTPN1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |