Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | PTPRZ1 | P23471 | 3/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
| ▸ | GCGR | P47871 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GIPR | P48546 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2541283 | 0.80 | KIF11 (0.54) | EPHX2NR1H4PTPRZ1KIF11PTPN1 | |
| SCHEMBL30745888 | 0.76 | EPHX2 (0.46) | EPHX2NR1H4PTPRZ1HDAC3HDAC1 | |
| SCHEMBL30745869 | 0.76 | EPHX2 (0.46) | EPHX2NR1H4PTPRZ1HDAC3HDAC1 | |
| SCHEMBL30745896 | 0.74 | HDAC1 (0.46) | EPHX2NR1H4PTPRZ1HDAC1KIF11 | |
| SCHEMBL30745904 | 0.73 | PTPRZ1 (0.72) | PTPRZ1PTPN1MAOB | |
| SCHEMBL4726846 | 0.72 | KIF11 (0.51) | EPHX2NR1H4PTPRZ1NR1H2NR1H3 | |
| Hydrochloric Acid SCHEMBL30745902 | 0.72 | PTPRZ1 (0.61) | EPHX2NR1H4PTPRZ1HDAC3HDAC1 | |
| SCHEMBL2283424 | 0.70 | EPHX2 (0.73) | EPHX2NR1H4PTPRZ1HDAC3HDAC1 | |
| SCHEMBL2913661 | 0.69 | HRH3 (0.52) | HDAC3ALDH1A1PLA2G10PLA2G2A | |
| SCHEMBL2745655 | 0.69 | TRPV1 (0.49) | EPHX2NR1H4PTPRZ1KIF11TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117682973-A | Sulfonamide compound and medical application thereof | 中国药科大学 | 2024-03-12 | — | — | CN | disclosed |