Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | QDPR | P09417 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27008011 | 0.87 | HSD11B1 (0.37) | HSD11B1ALDH1A1SMN1; SMN2QDPR | |
| Trifluoroacetic Acid SCHEMBL30745974 | 0.86 | HSD11B1 (0.38) | HSD11B1DGAT1 | |
| Trifluoroacetic Acid SCHEMBL30745997 | 0.80 | P2RY14 (0.41) | HSD11B1P2RY14QDPR | |
| SCHEMBL27007675 | 0.79 | HSD11B1 (0.43) | HSD11B1 | |
| Trifluoroacetic Acid SCHEMBL22638772 | 0.79 | P2RY14 (0.47) | P2RY14QDPR | |
| Trifluoroacetic Acid SCHEMBL27134405 | 0.79 | P2RY14 (0.41) | P2RY14QDPR | |
| Trifluoroacetic Acid SCHEMBL30746006 | 0.78 | PDE3B (0.51) | HSD11B1P2RY14QDPRDGAT1 | |
| Trifluoroacetic Acid SCHEMBL27126926 | 0.77 | ALOX5AP (0.41) | P2RY14QDPR | |
| Trifluoroacetic Acid SCHEMBL30745986 | 0.74 | CCNT1 (0.38) | P2RY14QDPR | |
| Trifluoroacetic Acid SCHEMBL27127184 | 0.74 | QDPR (0.43) | P2RY14QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | ERG28, CYP51A1, MANBA | HSD11B1 185/4885ALDH1A1 1109/4885CHRNA7 4829/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.