Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.41 |
| ▸ | KHK | P50053 | 4/20 | 0.39 |
| ▸ | HTR2C | P28335 | 4/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.38 |
| ▸ | QDPR | P09417 | 1/20 | 0.37 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30745990 | 0.99 | BRD4 (0.43) | BRD4HTR6KHKHTR2CSIGMAR1 | |
| SCHEMBL27007639 | 0.92 | HTR6 (0.45) | BRD4HTR6KHKHTR2CSIGMAR1 | |
| SCHEMBL27007956 | 0.92 | HTR6 (0.47) | BRD4HTR6KHKHTR2CSIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL30746015 | 0.87 | ALOX5AP (0.41) | KHKHTR2CSIGMAR1P2RY14ALOX5AP | |
| Trifluoroacetic Acid SCHEMBL30745992 | 0.87 | P2RY14 (0.41) | KHKHTR2CSIGMAR1P2RY14ALOX5AP | |
| Trifluoroacetic Acid SCHEMBL27126561 | 0.84 | ALOX5AP (0.39) | BRD4KHKHTR2CP2RY14ALOX5AP | |
| Trifluoroacetic Acid SCHEMBL27128175 | 0.84 | QDPR (0.39) | KHKHTR2CP2RY14ALOX5APFEN1 | |
| Trifluoroacetic Acid SCHEMBL27134405 | 0.84 | P2RY14 (0.41) | KHKHTR2CSIGMAR1P2RY14ALOX5AP | |
| Trifluoroacetic Acid SCHEMBL30746019 | 0.82 | P2RY14 (0.39) | KHKHTR2CSIGMAR1P2RY14ALOX5AP | |
| Trifluoroacetic Acid SCHEMBL27148687 | 0.81 | QDPR (0.37) | BRD4KHKHTR2CP2RY14ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | ERG28, CYP51A1, MANBA | BRD4 1389/4885HTR6 3566/4885KHK 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.