Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 6/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 3/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27007790 | 0.92 | PDE3B (0.53) | PDE3BPDE3AP2RY14HTR2CQDPR | |
| Trifluoroacetic Acid SCHEMBL30746008 | 0.88 | P2RY14 (0.42) | PDE3BPDE3AP2RY14HTR2CTBK1 | |
| Trifluoroacetic Acid SCHEMBL30745982 | 0.86 | QDPR (0.43) | PDE3BPDE3AP2RY14HTR2CTBK1 | |
| Trifluoroacetic Acid SCHEMBL30746002 | 0.82 | ALOX5AP (0.45) | PDE3BPDE3AP2RY14HTR2CTBK1 | |
| Trifluoroacetic Acid SCHEMBL30745987 | 0.80 | P2RY14 (0.40) | P2RY14HTR2CTBK1QDPRSIGMAR1 | |
| Trifluoroacetic Acid SCHEMBL30746006 | 0.80 | PDE3B (0.51) | PDE3BPDE3AP2RY14HTR2CQDPR | |
| Trifluoroacetic Acid SCHEMBL30746012 | 0.79 | CCNT1 (0.40) | PDE3BPDE3AP2RY14HTR2CTBK1 | |
| SCHEMBL27007732 | 0.77 | HTR2C (0.48) | HTR2CQDPRSIGMAR1NPC1TP53 | |
| SCHEMBL6586606 | 0.76 | HTR2C (0.60) | PDE3BPDE3AP2RY14HTR2CQDPR | |
| Trifluoroacetic Acid SCHEMBL27134849 | 0.75 | PDE3B (0.48) | PDE3BPDE3AP2RY14HTR2CQDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMCIAL DIVERSITY CENTER, INC. (US) | 2024-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018121-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | ERG28, CYP51A1, MANBA | PDE3B 1781/4885PDE3A 2859/4885P2RY14 3799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.