Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27264108 | 1.00 | MAOA (0.37) | MAOAMAOBELANEMPOCHRNA7 | |
| SCHEMBL30746092 | 0.84 | MAOA (0.37) | MAOAMAOBELANEMPOCHRNA7 | |
| SCHEMBL30746228 | 0.83 | MAOA (0.36) | MAOAMAOBCHRNA7ERN1REV1 | |
| SCHEMBL27264109 | 0.83 | MAOA (0.36) | MAOAMAOBCHRNA7ERN1REV1 | |
| SCHEMBL32666915 | 0.82 | EBP (0.42) | MAOAMAOBCHRNA7PTGDR2GYS1 | |
| SCHEMBL27264110 | 0.82 | EBP (0.42) | MAOAMAOBCHRNA7PTGDR2GYS1 | |
| SCHEMBL27261162 | 0.78 | MAOA (0.39) | MAOAMAOBELANEMPOREV1 | |
| SCHEMBL30769413 | 0.77 | MAOB (0.48) | MAOAMAOBELANEMPO | |
| SCHEMBL23740291 | 0.77 | MPO (0.49) | MAOAMAOBELANEMPOERN1 | |
| SCHEMBL30746172 | 0.75 | MAOB (0.46) | MAOAMAOBELANEMPOREV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554948-A1 | TETRAHYDRONAPHTHALENE DERIVATIVES AS ESTROGEN RECEPTOR DEGRADERS | Regents of the University of Michigan (US) | 2025-05-21 | — | — | EP | disclosed |