Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.48 |
| ▸ | MAOA | P21397 | 5/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.41 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30769328 | 0.90 | MPO (0.46) | MAOBMAOAMPOELANEHRH3 | |
| SCHEMBL23297253 | 0.85 | MPO (0.50) | MAOBMAOAMPOELANEHRH3 | |
| SCHEMBL23740291 | 0.84 | MPO (0.49) | MAOBMAOAMPOELANE | |
| SCHEMBL30723754 | 0.84 | MAOB (0.48) | MAOBMAOAMPOELANEHRH3 | |
| SCHEMBL28457075 | 0.83 | MAOB (0.46) | MAOBMAOAHRH3 | |
| SCHEMBL23740183 | 0.81 | MAOB (0.56) | MAOBMAOAHRH3 | |
| SCHEMBL27259828 | 0.81 | MAOB (0.46) | MAOBMAOAMPOELANEHRH3 | |
| SCHEMBL30746172 | 0.81 | MAOB (0.46) | MAOBMAOAMPOELANEHRH3 | |
| SCHEMBL30769387 | 0.80 | MPO (0.51) | MPOELANECYP24A1 | |
| SCHEMBL27261162 | 0.79 | MAOA (0.39) | MAOBMAOAMPOELANEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |