Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15018 | 0.89 | ALDH1A1 (0.42) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL166714 | 0.88 | NPC1 (0.41) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL543878 | 0.83 | TSHR (0.43) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL3074634 | 0.81 | NPC1 (0.39) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| Hexanoate SCHEMBL28167751 | 0.79 | ALDH1A1 (0.45) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL29942702 | 0.79 | ALDH1A1 (0.52) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL8950038 | 0.79 | ALDH1A1 (0.49) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL28330842 | 0.78 | TAAR1 (0.40) | TSHRCYP3A4ALDH1A1LMNAMEN1 | |
| SCHEMBL23058134 | 0.77 | TSHR (0.47) | TSHRALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL11216774 | 0.77 | CNR2 (0.43) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790081-B2 | Method of manufacturing formed product coated in mold | DAI NIPPON TORYO CO., LTD. (JP) | 2010-09-07 | — | — | US | disclosed |
| US-20050012241-A1 | Method of manufacturing formed product coated in mold | DAI NIPPON TORYO CO., LTD. (JP) | 2005-01-20 | — | — | US | disclosed |
| EP-0180789-B1 | CROSS-LINKING OF STYRENE POLYMERS | Luperox GmbH (DE) | 1990-02-28 | — | — | EP | disclosed |
| EP-0180789-A1 | Cross-linking of styrene polymers | Luperox GmbH (DE) | 1986-05-14 | — | — | EP | disclosed |