Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 4/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 6/20 | 0.32 |
| ▸ | KDR | P35968 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985087 | 1.00 | FPR2 (0.37) | FPR2AAK1SSTR4MAP2K1ABCB11 | |
| SCHEMBL26984982 | 0.96 | FPR2 (0.36) | FPR2AAK1SSTR4MAP2K1ABCB11 | |
| SCHEMBL30746395 | 0.93 | KDR (0.35) | FPR2AAK1MAP2K1ABCB11NQO2 | |
| SCHEMBL30746646 | 0.92 | MKNK1 (0.34) | AAK1SSTR4 | |
| SCHEMBL26984989 | 0.92 | MKNK1 (0.34) | AAK1SSTR4 | |
| SCHEMBL26985146 | 0.92 | SYK (0.35) | AAK1SSTR4MAP2K1MAP2K2HDAC3 | |
| SCHEMBL26985070 | 0.90 | NUDT1 (0.40) | AAK1MAP2K1KDR | |
| SCHEMBL30746399 | 0.89 | MAP2K2 (0.33) | MAP2K1MAP2K2 | |
| SCHEMBL30746634 | 0.89 | BRAF (0.34) | GAA | |
| SCHEMBL26984940 | 0.89 | BRAF (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |