Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 5/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | SYK | P43405 | 1/20 | 0.31 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984989 | 1.00 | MKNK1 (0.34) | MKNK1PIK3C3P2RY1THRBAAK1 | |
| SCHEMBL26985146 | 0.93 | SYK (0.35) | AAK1CSF1RSYKSSTR4DHODH | |
| SCHEMBL26985087 | 0.92 | FPR2 (0.37) | AAK1SSTR4 | |
| SCHEMBL26985070 | 0.92 | NUDT1 (0.40) | MKNK1AAK1CSF1RSYK | |
| SCHEMBL30746429 | 0.92 | FPR2 (0.37) | AAK1SSTR4 | |
| SCHEMBL30746634 | 0.91 | BRAF (0.34) | — | |
| SCHEMBL26984940 | 0.91 | BRAF (0.34) | — | |
| SCHEMBL26985244 | 0.91 | MAP2K2 (0.33) | SYKDHODH | |
| SCHEMBL30746399 | 0.91 | MAP2K2 (0.33) | SYKDHODH | |
| SCHEMBL30746639 | 0.90 | BACE1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |