Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 5/20 | 0.56 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.48 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | TLR4 | O00206 | 1/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26984900 | 1.00 | NUDT1 (0.56) | NUDT1TGFBR1CSF1RABL1EGFR | |
| SCHEMBL26985024 | 0.85 | NUDT1 (0.53) | NUDT1TGFBR1CSF1RABL1EGFR | |
| SCHEMBL30746560 | 0.85 | NUDT1 (0.53) | NUDT1TGFBR1CSF1RABL1EGFR | |
| SCHEMBL26985120 | 0.82 | KDM4E (0.45) | CSF1RKMT2ANPC1RAB9ARXFP1 | |
| SCHEMBL31613387 | 0.82 | KDM4E (0.45) | CSF1RKMT2ANPC1RAB9ARXFP1 | |
| SCHEMBL26984971 | 0.77 | NUDT1 (0.47) | NUDT1CSF1REGFRNPSR1KMT2A | |
| SCHEMBL30746519 | 0.77 | NUDT1 (0.47) | NUDT1CSF1REGFRNPSR1KMT2A | |
| SCHEMBL31613386 | 0.76 | NUDT1 (0.47) | NUDT1CSF1REGFRNPSR1KMT2A | |
| SCHEMBL30746528 | 0.76 | NUDT1 (0.47) | NUDT1CSF1REGFRMAP2K1NPSR1 | |
| SCHEMBL26985114 | 0.76 | NUDT1 (0.47) | NUDT1CSF1REGFRNPSR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |