Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 5/20 | 0.53 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.46 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.40 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.37 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985024 | 1.00 | NUDT1 (0.53) | NUDT1TGFBR1CSF1RACVR1BACVRL1 | |
| SCHEMBL30746391 | 0.87 | NUDT1 (0.53) | NUDT1TGFBR1CSF1RCNR2MAP2K1 | |
| SCHEMBL26985321 | 0.87 | NUDT1 (0.53) | NUDT1TGFBR1CSF1RCNR2MAP2K1 | |
| SCHEMBL26984900 | 0.85 | NUDT1 (0.56) | NUDT1TGFBR1CSF1RACVR1BACVRL1 | |
| SCHEMBL30746487 | 0.85 | NUDT1 (0.56) | NUDT1TGFBR1CSF1RACVR1BACVRL1 | |
| SCHEMBL30746686 | 0.76 | NUDT1 (0.43) | NUDT1CSF1REGFRCNR2MAP2K1 | |
| SCHEMBL26985203 | 0.76 | NUDT1 (0.43) | NUDT1CSF1REGFRCNR2MAP2K1 | |
| SCHEMBL30746436 | 0.74 | NUDT1 (0.40) | NUDT1EGFRCNR2FGFR1FLT1 | |
| SCHEMBL26985312 | 0.74 | NUDT1 (0.40) | NUDT1EGFRCNR2FGFR1FLT1 | |
| SCHEMBL15239842 | 0.73 | TGFBR1 (0.45) | NUDT1TGFBR1ABL1ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |