Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 6/20 | 0.38 |
| ▸ | FLT1 | P17948 | 5/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.38 |
| ▸ | FLT4 | P35916 | 2/20 | 0.37 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985148 | 1.00 | EGFR (0.39) | EGFRKDRFLT1NUDT1FGFR1 | |
| SCHEMBL30746656 | 0.84 | ALDH1A1 (0.42) | EGFRKDRFLT1NUDT1FGFR1 | |
| SCHEMBL26985170 | 0.84 | ALDH1A1 (0.42) | EGFRKDRFLT1NUDT1FGFR1 | |
| SCHEMBL30746601 | 0.81 | P2RX3 (0.40) | EGFRKDRFLT1NUDT1FGFR1 | |
| SCHEMBL26984883 | 0.81 | P2RX3 (0.40) | EGFRKDRFLT1NUDT1FGFR1 | |
| SCHEMBL26984976 | 0.80 | NUDT1 (0.38) | EGFRKDRFLT1NUDT1FGFR1 | |
| SCHEMBL30746381 | 0.80 | NUDT1 (0.38) | EGFRKDRFLT1NUDT1FGFR1 | |
| SCHEMBL31613381 | 0.79 | CYP17A1 (0.36) | NUDT1CSF1RCYP17A1HTT | |
| SCHEMBL26985334 | 0.78 | RAF1 (0.41) | KDRFLT1FGFR1SRCHTT | |
| SCHEMBL30746584 | 0.78 | NUDT1 (0.40) | KDRFLT1NUDT1FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |