Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 6/20 | 0.35 |
| ▸ | FLT1 | P17948 | 4/20 | 0.35 |
| ▸ | EGFR | P00533 | 3/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985203 | 1.00 | NUDT1 (0.43) | NUDT1KMT2ACNR2TRPM5MAP2K1 | |
| SCHEMBL30746436 | 0.88 | NUDT1 (0.40) | NUDT1KMT2ACNR2TRPM5KDR | |
| SCHEMBL26985312 | 0.88 | NUDT1 (0.40) | NUDT1KMT2ACNR2TRPM5KDR | |
| SCHEMBL26985139 | 0.82 | NUDT1 (0.47) | NUDT1KMT2ATRPM5MAP2K1KDR | |
| SCHEMBL30746528 | 0.82 | NUDT1 (0.47) | NUDT1KMT2ATRPM5MAP2K1KDR | |
| SCHEMBL26985321 | 0.79 | NUDT1 (0.53) | NUDT1KMT2ACNR2MAP2K1CSF1R | |
| SCHEMBL30746391 | 0.79 | NUDT1 (0.53) | NUDT1KMT2ACNR2MAP2K1CSF1R | |
| SCHEMBL30746627 | 0.78 | NUDT1 (0.39) | NUDT1KMT2ACNR2TRPM5MAP2K1 | |
| SCHEMBL26985082 | 0.78 | NUDT1 (0.39) | NUDT1KMT2ACNR2TRPM5MAP2K1 | |
| SCHEMBL30746560 | 0.76 | NUDT1 (0.53) | NUDT1CNR2MAP2K1KDRFLT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |