Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 4/20 | 0.53 |
| ▸ | MPO | P05164 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.38 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26985321 | 1.00 | NUDT1 (0.53) | NUDT1MPOTGFBR1KDM4CCNR2 | |
| SCHEMBL30746560 | 0.87 | NUDT1 (0.53) | NUDT1TGFBR1CNR2CSF1RMAP2K1 | |
| SCHEMBL26985024 | 0.87 | NUDT1 (0.53) | NUDT1TGFBR1CNR2CSF1RMAP2K1 | |
| SCHEMBL30746686 | 0.79 | NUDT1 (0.43) | NUDT1CNR2CSF1RKMT2AMAP2K1 | |
| SCHEMBL26985203 | 0.79 | NUDT1 (0.43) | NUDT1CNR2CSF1RKMT2AMAP2K1 | |
| SCHEMBL26985312 | 0.77 | NUDT1 (0.40) | NUDT1CNR2KMT2A | |
| SCHEMBL30746436 | 0.77 | NUDT1 (0.40) | NUDT1CNR2KMT2A | |
| SCHEMBL3379517 | 0.74 | CNR2 (0.63) | NUDT1CNR2 | |
| SCHEMBL30746487 | 0.73 | NUDT1 (0.56) | NUDT1TGFBR1CSF1RKMT2ANPC1 | |
| SCHEMBL29305777 | 0.73 | DUSP26 (0.46) | NUDT1MPOCNR2TAS2R14GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120129678-A | Mitogen-activated protein kinase (MEK) inhibitors | 耐斯泰德医疗公司 | 2025-06-10 | — | — | CN | disclosed |
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |