SCHEMBL3074679

SCHEMBL3074679

O=C(O)NC(=O)Oc1ccccc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
MAPT P10636 3/20 0.52
RAB9A P51151 1/20 0.50
RAD51 Q06609 1/20 0.50
NFKB1 P19838 1/20 0.49
NFKB2 Q00653 1/20 0.49
RELA Q04206 1/20 0.49
SLC1A3 P43003 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
KDM4E B2RXH2 2/20 0.47
THRB P10828 1/20 0.47
GFER P55789 1/20 0.47
GAA P10253 2/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HSD17B10 Q99714 3/20 0.46
LMNA P02545 1/20 0.46
TP53 P04637 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2551644 0.91 ALDH1A1 (0.55) ALDH1A1MAPTRAB9ARAD51NFKB1
SCHEMBL5279705 0.86 ALDH1A1 (0.52) ALDH1A1MAPTRAB9ARAD51NFKB1
SCHEMBL11525910 0.83 ALDH1A1 (0.49) ALDH1A1MAPTRAB9ARAD51NFKB1
SCHEMBL2186384 0.83 SLC1A3 (0.50) ALDH1A1MAPTRAB9ARAD51NFKB1
SCHEMBL26940022 0.83 ALDH1A1 (0.49) ALDH1A1MAPTRAB9ARAD51NFKB1
SCHEMBL23749590 0.83 ALDH1A1 (0.49) ALDH1A1MAPTRAB9ARAD51NFKB1
SCHEMBL16293318 0.83 ALDH1A1 (0.52) ALDH1A1MAPTRAB9ARAD51MEN1
SCHEMBL13019613 0.83 ALDH1A1 (0.62) ALDH1A1MAPTRAB9ARAD51NFKB1
SCHEMBL11525903 0.83 ALDH1A1 (0.49) ALDH1A1MAPTRAB9ARAD51NFKB1
SCHEMBL3063928 0.81 NFKB1 (0.49) ALDH1A1MAPTRAB9ARAD51NFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022226182-A1 NEK7 INHIBITORS Halia Therapeutics, Inc. (US) 2022-10-27 WO disclosed
CN-113939520-A Thiazolopyridine derivatives as adenosine receptor antagonists 默克专利股份公司 2022-01-14 CN disclosed
EP-3334733-A1 3-INDOL SUBSTITUTED DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE Pfizer Inc (US) 2018-06-20 EP disclosed
WO-2017025868-A1 3-INDOL SUBSTITUTED DERIVATIVES, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR USE PFIZER INC. (US) 2017-02-16 WO disclosed
CN-101454311-B Salt of phenoxypyridine derivative, crystal thereof and process for producing the same EISAI R&D MAN CO LTD 2013-03-27 CN disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 US disclosed
CN-101454311-A Salt of phenoxypyridine derivative, crystal thereof and process for producing the same EISAI R&D MAN CO LTD (JP) 2009-06-10 CN disclosed
US-7422793-B2 Non-toxic corrosion-protection rinses and seals based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-09-09 US disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 WO disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 US disclosed
US-20040020568-A1 Non-toxic corrosion-protection conversion coats based on rare earth elements DAYTON, UNIVERSITY OF 2004-02-05 US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
US-5189058-A Anticholesterol agents WARNER-LAMBERT COMPANY (US) 1993-02-23 US disclosed
US-4555405-A INSECTICIDE, MITICIDE CIBA GEIGY CORPORATION (US) 1985-11-26 US disclosed