Sugi Predict

Sugi Predict / Compounds / SCHEMBL2551644

SCHEMBL2551644

SCHEMBL2551644

O=C(NC(=O)Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 6/20 0.55
▸ MAPT P10636 3/20 0.55
▸ RAB9A P51151 1/20 0.53
▸ RAD51 Q06609 1/20 0.53
▸ SLC1A3 P43003 1/20 0.52
▸ NFKB1 P19838 1/20 0.51
▸ NFKB2 Q00653 1/20 0.51
▸ RELA Q04206 1/20 0.51
▸ GAA P10253 2/20 0.50
▸ MEN1 O00255 2/20 0.50
▸ KMT2A Q03164 2/20 0.50
▸ TDP1 Q9NUW8 2/20 0.50
▸ KDM4E B2RXH2 2/20 0.50
▸ HTT P42858 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ THRB P10828 1/20 0.50
▸ GFER P55789 1/20 0.50
▸ HSD17B10 Q99714 2/20 0.49
▸ LMNA P02545 1/20 0.49
▸ TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3074679 0.91 ALDH1A1 (0.52) ALDH1A1MAPTRAB9ARAD51SLC1A3
SCHEMBL5279705 0.91 ALDH1A1 (0.52) ALDH1A1MAPTRAB9ARAD51SLC1A3
SCHEMBL11525910 0.87 ALDH1A1 (0.49) ALDH1A1MAPTRAB9ARAD51SLC1A3
SCHEMBL13019613 0.87 ALDH1A1 (0.62) ALDH1A1MAPTRAB9ARAD51SLC1A3
SCHEMBL26940022 0.87 ALDH1A1 (0.49) ALDH1A1MAPTRAB9ARAD51SLC1A3
SCHEMBL23749590 0.87 ALDH1A1 (0.49) ALDH1A1MAPTRAB9ARAD51SLC1A3
SCHEMBL2186384 0.87 SLC1A3 (0.50) ALDH1A1MAPTRAB9ARAD51SLC1A3
SCHEMBL16293318 0.87 ALDH1A1 (0.52) ALDH1A1MAPTRAB9ARAD51MEN1
SCHEMBL11525903 0.87 ALDH1A1 (0.49) ALDH1A1MAPTRAB9ARAD51SLC1A3
SCHEMBL3063928 0.85 NFKB1 (0.49) ALDH1A1MAPTRAB9ARAD51SLC1A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12404253-B2 2,4,6-trisubstituted 1,3,5-triazines as modulators of CX3CR1 ASTRAZENECA AB (SE) 2025-09-02 — — US disclosed
EP-4605388-A1 <SUP2/>? <SUB2/>?3?2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CXCR1 Astrazeneca AB (SE) 2025-08-27 — — EP disclosed
CN-120077035-A As CX32,4, 6-Trisubstituted 1,3, 5-triazines as modulators of CR1 阿斯利康(瑞典)有限公司 2025-05-30 — — CN disclosed
US-20240383866-A1 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 ASTRAZENECA AB (SE) 2024-11-21 — — US disclosed
US-20240199558-A1 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 ASTRAZENECA AB (SE) 2024-06-20 — — US disclosed
WO-2024083933-A1 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX 3CR1 ASTRAZENECA AB (SE) 2024-04-25 — — WO disclosed
EP-3227287-B1 HETEROARYL-SUBSTITUTED IMIDAZO[1,2-A]PYRIDINES AND THEIR USE Bayer Pharma AG (DE) 2019-08-07 — — EP disclosed
CN-109641915-A Novel 4- (aryl)-N- (3- alkoxy furans simultaneously [2,3-B] pyrazine -2- base)-piperazine -1- carboxamides derivatives and its antiproliferative effect 东国大学校产学协力团 2019-04-16 — — CN disclosed
US-10000471-B2 Pyrazole P38 map kinase inhibitors RESPIVERT LIMITED (GB) 2018-06-19 — — US disclosed
US-20170362208-A1 NOVEL COMPOUNDS RESPIVERT LIMITED (GB) 2017-12-21 — — US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 — — US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 — — US disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
EP-0401707-B1 Heterocyclic triazin or triazolo compounds having serotonin 2-receptor antagonistic activity DAIICHI SEIYAKU CO (JP) 1994-09-21 — — EP disclosed
US-5281625-A Benzyl substituted guanidine derivatives, salts, and metal complexes BASF AKTIENGESELLSCHAFT (DE) 1994-01-25 — — US disclosed
US-5232924-A Cardiovascular disorders DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1993-08-03 — — US disclosed
US-5126374-A For plants, seeds, soils, effective at low concentrations BASF AKTIENGESELLSCHAFT (DE) 1992-06-30 — — US disclosed
CN-1049161-A Heterogeneous ring compound with serotonine 2-receptor antagonistic activity DAIICHI SEIYAKU CO (JP) 1991-02-13 — — CN disclosed
EP-0401707-A1 Heterocyclic triazin or triazolo compounds having serotonin 2-receptor antagonistic activity DAIICHI PHARMACEUTICAL CO., LTD. (JP) 1990-12-12 — — EP disclosed
EP-0154906-A2 3-Cyclopropylmethyl-1,3,5-triazine-2,4-dione BAYER AG (DE) 1985-09-18 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199558-A1 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 CX3CR1, CCR2, CCR5 ALDH1A1 1531/4885MAPT 2407/4885RAB9A 3982/4885
US-20240383866-A1 2,4,6-TRISUBSTITUTED 1,3,5-TRIAZINES AS MODULATORS OF CX3CR1 CX3CR1, CCR2, CCR5 ALDH1A1 1531/4885MAPT 2407/4885RAB9A 3982/4885
US-20170362208-A1 NOVEL COMPOUNDS ARG1, IL1B, LTB4R ALDH1A1 755/4885MAPT 2621/4885RAB9A 1341/4885
US-10000471-B2 Pyrazole P38 map kinase inhibitors MAPK1, MAP3K1, MAPK3 ALDH1A1 1809/4885MAPT 1600/4885RAB9A 1137/4885
US-12404253-B2 2,4,6-trisubstituted 1,3,5-triazines as modulators of CX3CR1 CX3CR1, CCR2, CCR5 ALDH1A1 1531/4885MAPT 2407/4885RAB9A 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.