Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PARG | Q86W56 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6877063 | 0.79 | KMT2A (0.42) | KMT2ARAB9AMEN1SMN1; SMN2POLB | |
| SCHEMBL8070347 | 0.78 | SIGMAR1 (0.41) | KMT2ARAB9AMEN1SMN1; SMN2POLB | |
| SCHEMBL15244381 | 0.77 | F10 (0.40) | KMT2APOLBLMNA | |
| SCHEMBL176995 | 0.76 | POLB (0.44) | KMT2ARAB9AMEN1SMN1; SMN2POLB | |
| SCHEMBL3553015 | 0.76 | POLB (0.40) | KMT2AMEN1POLB | |
| SCHEMBL3452808 | 0.75 | TSHR (0.50) | KMT2ARAB9AMEN1SMN1; SMN2POLB | |
| SCHEMBL15244380 | 0.74 | SMN1; SMN2 (0.58) | KMT2ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL10542255 | 0.74 | NAAA (0.48) | NAAA | |
| SCHEMBL6287476 | 0.73 | KMT2A (0.41) | KMT2ARAB9AMEN1SMN1; SMN2POLB | |
| SCHEMBL13853727 | 0.73 | KMT2A (0.59) | KMT2ARAB9AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522596-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X Discovery Limited (GB) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023218203-A1 | DIHYDROINDENE DERIVATIVES AS MALT1 INHIBITORS | C4X DISCOVERY LIMITED (GB) | 2023-11-16 | — | — | WO | disclosed |