Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 4/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748129 | 0.78 | KMT2A (0.42) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL6877063 | 0.72 | KMT2A (0.42) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL3579845 | 0.71 | PLA2G10 (0.46) | KMT2ARAB9ASCN9AALDH1A1KDM4E | |
| SCHEMBL176995 | 0.70 | POLB (0.44) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL8063156 | 0.69 | ALDH1A1 (0.60) | SIGMAR1KMT2ARAB9AALDH1A1KDM4E | |
| SCHEMBL28931873 | 0.69 | FAAH (0.51) | RAB9AALDH1A1PARGFAAHNAAA | |
| SCHEMBL6283661 | 0.69 | KMT2A (0.37) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL15964104 | 0.69 | KMT2A (0.57) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL3452808 | 0.69 | TSHR (0.50) | KMT2ARAB9AALDH1A1KDM4ELMNA | |
| SCHEMBL18177907 | 0.68 | ALDH1A1 (0.63) | SIGMAR1KMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080132500-A1 | Antibiotic compounds | MERCK SHARP & DOHME CORP. | 2008-06-05 | — | — | US | disclosed |
| US-20080132500-A1 | Antibiotic compounds | MERCK SHARP & DOHME CORP. | 2008-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080132500-A1 | Antibiotic compounds | NRDC, MRPL21, PEPD | SIGMAR1 2910/4885KMT2A 4616/4885RAB9A 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.