Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24631538 | 1.00 | KMT2A (0.50) | KMT2AALDH1A1CTNNB1KDM4ELMNA | |
| SCHEMBL2864968 | 0.86 | CTNNB1 (0.51) | ALDH1A1CTNNB1KDM4EHTR1ASLC6A2 | |
| SCHEMBL30775056 | 0.86 | CTNNB1 (0.51) | ALDH1A1CTNNB1KDM4EHTR1ASLC6A2 | |
| SCHEMBL19524204 | 0.83 | SCN8A (0.53) | KMT2AALDH1A1CTNNB1KDM4ELMNA | |
| SCHEMBL19524223 | 0.83 | SCN8A (0.56) | KMT2ACTNNB1KDM4ELMNASLC6A4 | |
| SCHEMBL11455143 | 0.81 | SMN1; SMN2 (0.54) | KMT2AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL3179214 | 0.81 | CTNNB1 (0.67) | KMT2AALDH1A1CTNNB1KDM4ELMNA | |
| SCHEMBL29679671 | 0.81 | CTNNB1 (0.67) | KMT2AALDH1A1CTNNB1KDM4ELMNA | |
| SCHEMBL27679500 | 0.81 | LMNA (0.55) | ALDH1A1CTNNB1KDM4ELMNAMAPT | |
| SCHEMBL22719512 | 0.81 | RXFP1 (0.57) | MAPTRAB9AMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279632-A | TAAR1 and serotonin modulators, pharmaceutical compositions thereof, and methods of use | 赛诺维信制药公司 | 2023-12-22 | — | — | CN | disclosed |