Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 2/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10958981 | 0.82 | LMNA (0.38) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL6124172 | 0.79 | TYR (0.41) | LMNAKMT2AALDH1A1IDO1TDO2 | |
| SCHEMBL30748244 | 0.74 | ALDH1A1 (0.37) | ALDH1A1TSHRIDO1TDO2HTT | |
| SCHEMBL29131868 | 0.72 | TSHR (0.44) | TSHRIDO1TDO2ATML3MBTL1 | |
| SCHEMBL8402080 | 0.72 | ATM (0.36) | LMNAKMT2AATML3MBTL1 | |
| SCHEMBL8406168 | 0.72 | ATM (0.36) | LMNAKMT2AATML3MBTL1 | |
| SCHEMBL4583472 | 0.72 | ATM (0.36) | LMNAKMT2AATML3MBTL1 | |
| SCHEMBL6124179 | 0.71 | SLC6A3 (0.45) | LMNAKMT2AALDH1A1IDO1TDO2 | |
| SCHEMBL6421761 | 0.71 | LMNA (0.39) | LMNAKMT2AMEN1THRBBLM | |
| SCHEMBL29565971 | 0.71 | ALDH1A1 (0.38) | ALDH1A1TSHRIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117279632-A | TAAR1 and serotonin modulators, pharmaceutical compositions thereof, and methods of use | 赛诺维信制药公司 | 2023-12-22 | — | — | CN | disclosed |