Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF18A | Q8NI77 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26650561 | 1.00 | KIF18A (0.72) | KIF18A | |
| SCHEMBL26650648 | 0.88 | KIF18A (0.70) | KIF18A | |
| SCHEMBL30748572 | 0.88 | KIF18A (0.70) | KIF18A | |
| SCHEMBL26650663 | 0.87 | KIF18A (0.75) | KIF18A | |
| SCHEMBL31485375 | 0.87 | KIF18A (0.75) | KIF18A | |
| SCHEMBL30748601 | 0.85 | KIF18A (0.69) | KIF18A | |
| SCHEMBL29370333 | 0.84 | KIF18A (1.00) | KIF18A | |
| SCHEMBL22148255 | 0.84 | KIF18A (1.00) | KIF18A | |
| SCHEMBL30748590 | 0.83 | KIF18A (0.71) | KIF18A | |
| SCHEMBL22152140 | 0.83 | KIF18A (1.00) | KIF18A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4524135-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | Shanghai Apeiron Therapeutics Company Limited (CN) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |