Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 6/20 | 0.49 |
| ▸ | MKNK2 | Q9HBH9 | 6/20 | 0.49 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | PLK1 | P53350 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24021437 | 0.77 | HTT (0.64) | RIPK1ARNPC1RAB9APOLB | |
| SCHEMBL29845556 | 0.77 | HTT (0.64) | RIPK1ARNPC1RAB9APOLB | |
| SCHEMBL249349 | 0.77 | HTT (0.64) | RIPK1ARNPC1RAB9APOLB | |
| Hydrochloric Acid SCHEMBL3701824 | 0.75 | HTT (0.62) | RIPK1ARNPC1RAB9APOLB | |
| SCHEMBL7145196 | 0.75 | LCK (0.47) | ARNPC1RAB9APOLBALOX15 | |
| SCHEMBL2232014 | 0.73 | ALDH1A1 (0.55) | RIPK1ARMKNK1MKNK2ALOX15 | |
| SCHEMBL31068033 | 0.73 | ALDH1A1 (0.55) | RIPK1ARMKNK1MKNK2ALOX15 | |
| Quinoline SCHEMBL28128756 | 0.73 | HTT (0.59) | ARNPC1CHEK2RAB9APOLB | |
| Hydrochloric Acid SCHEMBL28060868 | 0.72 | MEN1 (0.53) | RIPK1ARMKNK1MKNK2TRPV1 | |
| SCHEMBL26613435 | 0.72 | CA12 (0.60) | RIPK1MKNK1MKNK2MAP4K4CHEK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023217230-A1 | KINESIN KIF18A INHIBITOR AND USE THEREOF | 上海湃隆生物科技有限公司 | 2023-11-16 | — | — | WO | disclosed |