SCHEMBL30748754

SCHEMBL30748754

CC1(C)C(=O)N(c2ccc(N3CCOCC3)cc2)c2nc(CO)nc(N)c21

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.36
LGMN Q99538 3/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
DGAT1 O75907 1/20 0.35
TLR7 Q9NYK1 1/20 0.35
PIK3CA P42336 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
USP2 O75604 1/20 0.35
TP53 P04637 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
HSD17B10 Q99714 1/20 0.35
AGXT P21549 1/20 0.34
AOC3 Q16853 2/20 0.34
CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748787 0.86 L3MBTL1 (0.36) L3MBTL1PIK3CAALDH1A1MAPTKMT2A
SCHEMBL30748933 0.85 SYK (0.40) L3MBTL1ALDH1A1MAPTKDM4EALOX15
SCHEMBL30749038 0.85 ADORA3 (0.39) L3MBTL1PIK3CAALDH1A1MAPTKDM4E
SCHEMBL30748952 0.83 SYK (0.37) L3MBTL1TLR7ALDH1A1MAPTSMN1; SMN2
SCHEMBL30748935 0.83 AGXT (0.37) XDHLGMNDGAT1TLR7ALDH1A1
SCHEMBL30749016 0.81 SYK (0.36) L3MBTL1ALDH1A1
SCHEMBL30748928 0.76 MAPT (0.34) L3MBTL1MAPTKMT2AKDM4EMEN1
SCHEMBL30748781 0.76 AOC3 (0.39) PIK3CAALDH1A1MAPTKMT2AMEN1
SCHEMBL30749110 0.74 MAPT (0.33) L3MBTL1ALDH1A1MAPTKMT2AKDM4E
SCHEMBL31691354 0.71 AGXT (0.33) L3MBTL1ALDH1A1MAPTKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT XDH 404/4885LGMN 334/4885L3MBTL1 517/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.