SCHEMBL30748909

SCHEMBL30748909

CC1(C)CN(c2ccc(OC3CCCCC3)nc2)c2nc(CO)ncc21

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ACACB O00763 5/20 0.37
CHRM4 P08173 1/20 0.36
P2RX3 P56373 4/20 0.32
FLT3 P36888 2/20 0.31
PDGFRB P09619 1/20 0.31
PDGFRA P16234 1/20 0.31
HRH3 Q9Y5N1 1/20 0.31
LCAT P04180 1/20 0.31
LOX P28300 1/20 0.30
LOXL2 Q9Y4K0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30749128 0.80 CHRM4 (0.40) ACACBCHRM4PDGFRBPDGFRA
SCHEMBL30748796 0.80 CHRM4 (0.33) CHRM4P2RX3
SCHEMBL30748908 0.78 ACACB (0.37) ACACBCHRM4P2RX3HRH3LCAT
SCHEMBL30748881 0.77 PIK3CA (0.38) ACACBCHRM4HRH3
SCHEMBL30749098 0.77 CCNE1 (0.36) ACACBCHRM4P2RX3HRH3LCAT
SCHEMBL30748804 0.75 ACACB (0.38) ACACBCHRM4P2RX3FLT3HRH3
SCHEMBL30748853 0.72 POLB (0.36)
SCHEMBL30748874 0.72 CHRM4 (0.45) ACACBCHRM4P2RX3HRH3LCAT
SCHEMBL30748954 0.72 CDK2 (0.37) ACACBCHRM4HRH3
SCHEMBL30749053 0.71 ALDH1A1 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT ACACB 1127/4885CHRM4 4607/4885P2RX3 1730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.