SCHEMBL30748844

SCHEMBL30748844

O=C1Cc2cnc(Cl)nc2N1c1ccc(OC2CCCC2)nc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AR P10275 4/20 0.35
HRH3 Q9Y5N1 6/20 0.34
ACACB O00763 3/20 0.33
BTK Q06187 1/20 0.33
FPR2 P25090 1/20 0.32
PROKR1 Q8TCW9 1/20 0.32
LCAT P04180 1/20 0.32
KCNH2 Q12809 1/20 0.32
NAMPT P43490 2/20 0.32
P2RX3 P56373 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30749141 0.96 AR (0.34) ARHRH3ACACBBTKFPR2
SCHEMBL30748799 0.83 ACACB (0.34) ARHRH3ACACBBTKFPR2
SCHEMBL30748875 0.80 LIPE (0.36) ACACBLCATP2RX3
SCHEMBL30748958 0.78 AR (0.38) ARHRH3ACACBBTKFPR2
SCHEMBL30748806 0.77 AR (0.38) ARHRH3ACACBBTKFPR2
SCHEMBL30748997 0.74 ACACB (0.37) ARHRH3ACACBBTKFPR2
SCHEMBL30748803 0.73 CCNE1 (0.39) ARHRH3ACACBBTKFPR2
SCHEMBL30748879 0.71 ALDH1A1 (0.44)
SCHEMBL31691281 0.70 AVPR1A (0.41) KCNH2
SCHEMBL30748972 0.70 PSEN1 (0.40) HRH3ACACB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT AR 57/4885HRH3 4719/4885ACACB 1127/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.