SCHEMBL30748977

SCHEMBL30748977

CC1(C)OB(c2cc(F)c3c(c2)CCCO3)OC1(C)C

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.36
LIPG Q9Y5X9 3/20 0.36
ROCK1 Q13464 1/20 0.36
P2RX7 Q99572 1/20 0.34
MAPK1 P28482 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15634931 1.00 LPL (0.36) LPLLIPGROCK1P2RX7MAPK1
SCHEMBL31394217 0.91 LPL (0.38) LPLLIPGROCK1P2RX7MAPK1
SCHEMBL14746201 0.83 NOTUM (0.40) LPLLIPGP2RX7MAPK1
SCHEMBL27160138 0.79 P2RX7 (0.31) P2RX7MAPK1
SCHEMBL10159268 0.78 P2RX7 (0.38) LPLLIPGP2RX7MAPK1
SCHEMBL15335297 0.78 LPL (0.39) LPLLIPGROCK1P2RX7MAPK1
SCHEMBL27159643 0.78 HTR1D (0.31) P2RX7
SCHEMBL29914826 0.78 HTR1D (0.31) P2RX7
SCHEMBL13035937 0.76 LPL (0.36) LPLLIPGROCK1
SCHEMBL10211769 0.76 LPL (0.36) LPLLIPGROCK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed