Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.32 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30748990 | 0.88 | MEN1 (0.31) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30748943 | 0.78 | — | — | |
| SCHEMBL30748737 | 0.72 | — | — | |
| SCHEMBL30749132 | 0.71 | RAB9A (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL82980 | 0.68 | NPC1 (0.46) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL82981 | 0.68 | NPC1 (0.46) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL30749100 | 0.67 | PRKDC (0.42) | ALDH1A1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL30749116 | 0.65 | ACACB (0.37) | — | |
| SCHEMBL30748905 | 0.64 | ACACB (0.45) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD | |
| SCHEMBL29455297 | 0.64 | NPC1 (0.41) | NPC1ALDH1A1RAB9ASMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565588-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | Suzhou Keen Therapeutics Co., Ltd. (CN) | 2025-06-11 | — | — | EP | disclosed |
| WO-2023241620-A1 | BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF | SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) | 2023-12-21 | — | — | WO | disclosed |