SCHEMBL30749100

SCHEMBL30749100

CC1(C)C(=O)N(c2ccc(N3CCOCC3)cc2)c2ncnc(Cl)c21

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 4/20 0.42
RAD51 Q06609 2/20 0.39
ELANE P08246 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
RAB9A P51151 1/20 0.37
DGAT1 O75907 1/20 0.37
PIK3CD O00329 1/20 0.37
PIK3CA P42336 1/20 0.37
PIK3CB P42338 1/20 0.37
PTK2 Q05397 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748722 0.84 TTBK1 (0.38) PRKDCALDH1A1MAPTSMN1; SMN2RAB9A
SCHEMBL30748915 0.81 ADORA3 (0.40) PRKDCALDH1A1MAPTRAB9A
SCHEMBL30749083 0.74 ACACB (0.38) ELANEALDH1A1MEN1KMT2A
SCHEMBL30749132 0.74 RAB9A (0.41) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL30748783 0.73 AGXT (0.34) RAD51ALDH1A1MEN1KMT2AMAPT
SCHEMBL30748904 0.72 RAD51 (0.42) RAD51ALDH1A1SMN1; SMN2
SCHEMBL30748754 0.70 XDH (0.36) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL30749140 0.68 MAPT (0.39) RAD51ALDH1A1MEN1KMT2AMAPT
SCHEMBL5177701 0.68 AR (0.55) ALDH1A1MEN1KMT2AMAPTSMN1; SMN2
SCHEMBL30748777 0.67 PRKDC (0.39) PRKDCRAD51ALDH1A1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed