SCHEMBL30749050

SCHEMBL30749050

O=C1N(c2ccc(F)c(F)c2)c2nc(CO)nc(NC3CC3)c2C12CCCC2

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.32
PDE4B Q07343 2/20 0.32
PDE4D Q08499 2/20 0.32
GPR6 P46095 2/20 0.31
KCNQ3 O43525 1/20 0.31
KCNQ2 O43526 1/20 0.31
MEN1 O00255 2/20 0.30
ALDH1A1 P00352 2/20 0.30
KMT2A Q03164 2/20 0.30
MMP13 P45452 1/20 0.30
ADAMTS5 Q9UNA0 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
CHRM3 P20309 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4C Q08493 1/20 0.30
HTR1A P08908 1/20 0.30
DRD2 P14416 1/20 0.30
ADRA1D P25100 1/20 0.30
ADRA1A P35348 1/20 0.30
ADRA1B P35368 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30748971 0.86 MAOB (0.40)
SCHEMBL31691412 0.84 AR (0.30) AR
SCHEMBL30748855 0.82 SYK (0.39) MEN1KMT2AADORA3
SCHEMBL31691422 0.78 CHRM3 (0.37) PDE4BPDE4DMEN1ALDH1A1KMT2A
SCHEMBL30749139 0.74 MAOB (0.41) ALDH1A1
SCHEMBL30749004 0.72 HDAC6 (0.33) MEN1ALDH1A1KMT2A
SCHEMBL30748982 0.72 PGR (0.37) ARMEN1ALDH1A1KMT2AHTR1A
SCHEMBL31691331 0.68 SYK (0.36) MEN1KMT2AADORA3
SCHEMBL31691203 0.67 KMT2A (0.31) ARKMT2A
SCHEMBL31691360 0.66 TTK (0.33) MEN1KMT2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT AR 57/4885PDE4B 2287/4885PDE4D 2264/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.