SCHEMBL30748982

SCHEMBL30748982

O=C1N(c2ccc(F)c(F)c2)c2nc(Cl)nc(Cl)c2C12CCCC2

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PGR P06401 2/20 0.37
AR P10275 2/20 0.36
RAD51 Q06609 1/20 0.36
CYP11B2 P19099 2/20 0.34
HTR1A P08908 1/20 0.33
DRD2 P14416 1/20 0.33
ADRA1D P25100 1/20 0.33
ADRA1A P35348 1/20 0.33
ADRA1B P35368 1/20 0.33
KMT2A Q03164 2/20 0.32
CNR1 P21554 3/20 0.31
CNR2 P34972 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.30
ALOX15 P16050 1/20 0.30
TSHR P16473 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31691203 0.80 KMT2A (0.31) ARRAD51KMT2A
SCHEMBL30749140 0.78 MAPT (0.39) PGRRAD51KMT2ACNR2MEN1
SCHEMBL31627095 0.77
SCHEMBL31626913 0.73 ALOX5AP (0.36) PGR
SCHEMBL30749044 0.72 ALDH1A1 (0.34) PGRALDH1A1TSHR
SCHEMBL30749050 0.72 AR (0.32) ARHTR1ADRD2ADRA1DADRA1A
SCHEMBL30748771 0.69 KMT2A (0.36) ADRA1AKMT2AMEN1
SCHEMBL31691410 0.68 MTOR (0.31)
SCHEMBL30748824 0.68 KMT2A (0.37) ADRA1AKMT2A
SCHEMBL30748904 0.68 RAD51 (0.42) RAD51ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2025-10-02 US disclosed
EP-4565588-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF Suzhou Keen Therapeutics Co., Ltd. (CN) 2025-06-11 EP disclosed
WO-2023241620-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF SUZHOU KEEN THERAPEUTICS CO., LTD. (CN) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250304571-A1 BIOLOGICALLY ACTIVE COMPOUNDS AND METHODS THEREOF VHL, BRCA1, TERT PGR 499/4885AR 57/4885RAD51 2049/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.