SCHEMBL3074916

SCHEMBL3074916

NC(CC(=O)O)(CC(=O)O)P(=O)(O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 6/20 0.38
TSHR P16473 2/20 0.38
LMNA P02545 2/20 0.38
TDP1 Q9NUW8 2/20 0.38
MEN1 O00255 1/20 0.38
HPGD P15428 1/20 0.38
BLM P54132 1/20 0.38
KMT2A Q03164 1/20 0.38
ALDH1A1 P00352 1/20 0.36
HMGCR P04035 1/20 0.36
CHRM1 P11229 1/20 0.36
TBXA2R P21731 1/20 0.36
ADRA1A P35348 1/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP2D6 P10635 1/20 0.35
CYP2C19 P33261 1/20 0.35
HIF1A Q16665 1/20 0.35
ADRB3 P13945 1/20 0.32
PDE4D Q08499 1/20 0.32
PDE3A Q14432 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11303562 0.79 FDPS (0.46) FDPSTSHRLMNATDP1MEN1
SCHEMBL9308664 0.75 FDPS (0.46) FDPSTSHRLMNATDP1MEN1
SCHEMBL6669718 0.72 FDPS (0.46) FDPSTSHRLMNATDP1MEN1
Oxalic Acid SCHEMBL1378538 0.70 FDPS (0.43) FDPSLMNAMEN1KMT2AALDH1A1
SCHEMBL6141877 0.68 ALDH1A1 (0.42) TSHRLMNATDP1MEN1HPGD
SCHEMBL10903812 0.68 HMGCR (0.48) FDPSTSHRLMNATDP1MEN1
SCHEMBL5691553 0.68 ALDH1A1 (0.42) TSHRLMNATDP1MEN1HPGD
SCHEMBL10589741 0.67
SCHEMBL16374685 0.67 ALDH1A1 (0.45) TSHRLMNATDP1ALDH1A1HMGCR
SCHEMBL26361 0.67 ALDH1A1 (0.45) TSHRLMNATDP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7790025-B2 External gradient chromatofocusing CRYOBIOPHYSICA, INC. (US) 2010-09-07 US disclosed
US-20070144973-A1 External gradient chromatofocusing CRYOBIOPHYSICA, INC. (US) 2007-06-28 US disclosed
EP-1628729-A2 EXTERNAL GRADIENT CHROMATOFOCUSING Cryobiophysica, Inc. (US) 2006-03-01 EP disclosed
WO-2004103519-A2 EXTERNAL GRADIENT CHROMATOFOCUSING CRYOBIOPHYSICA, INC. (US) 2004-12-02 WO disclosed
US-4405418-A PURIFICATION OF SODIUM CHLORIDE ELECTROLYTE WITH CHELATING ION EXCHANGE RESIN OF CROSSLINKED CHLOROMETHYLSTYRENE-DIVINYLBENZENE COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-09-20 US disclosed
US-4261803-A MAINTAINING LOW CONCENTRATION OF CALCIUM AND MAGNESIUM IONS ASAHI GLASS COMPANY, LTD. (JP) 1981-04-14 US disclosed
EP-0013309-A1 Electrolysis of aqueous solution of potassium chloride ASAHI GLASS COMPANY LTD. (JP) 1980-07-23 EP disclosed
US-4202743-A FLUORINATED CATION EXCHANGE MEMBRANE ASAHI GLASS COMPANY, LIMITED (JP) 1980-05-13 US disclosed