Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | CPT2 | P23786 | 2/20 | 0.36 |
| ▸ | CPT1A | P50416 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224058 | 0.99 | ALDH1A1 (0.39) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27224042 | 0.90 | KMT2A (0.46) | ALOX15ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30749254 | 0.90 | KMT2A (0.46) | ALOX15ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL30749239 | 0.89 | KMT2A (0.47) | ALOX15ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27223426 | 0.89 | KMT2A (0.47) | ALOX15ALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27223533 | 0.87 | F2 (0.41) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27223361 | 0.85 | OPRK1 (0.36) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27224205 | 0.85 | ALDH1A1 (0.44) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27223421 | 0.85 | ALDH1A1 (0.44) | ALOX15ALDH1A1HPGDHSD17B10KDM4E | |
| Hydrochloric Acid SCHEMBL30749296 | 0.85 | KMT2A (0.41) | ALOX15ALDH1A1KDM4ECPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166642-A1 | INHIBITORS OF MYELOPEROXIDASE | MPO, XDH, EPX | ALOX15 557/4885ALDH1A1 502/4885HPGD 572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.