Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | F9 | P00740 | 2/20 | 0.35 |
| ▸ | F10 | P00742 | 2/20 | 0.35 |
| ▸ | F12 | P00748 | 2/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.35 |
| ▸ | F7 | P08709 | 2/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.35 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27224063 | 1.00 | ALOX15 (0.39) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27224141 | 0.90 | ALDH1A1 (0.38) | ALOX15ALDH1A1LMNAMAPTTSHR | |
| SCHEMBL31556733 | 0.89 | MEN1 (0.40) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27224083 | 0.89 | ALDH1A1 (0.47) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL30028767 | 0.89 | ALDH1A1 (0.47) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL30749240 | 0.89 | MEN1 (0.40) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL30749308 | 0.89 | ALDH1A1 (0.45) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27224054 | 0.89 | ALDH1A1 (0.45) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL30749326 | 0.80 | ALDH1A1 (0.40) | ALOX15ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL27223533 | 0.79 | F2 (0.41) | ALOX15ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| CN-119894896-A | Inhibitors of green peroxidase | 阿斯利康(瑞典)有限公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |