Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | AHCY | P23526 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30028767 | 0.90 | ALDH1A1 (0.47) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL27224083 | 0.90 | ALDH1A1 (0.47) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL27224054 | 0.88 | ALDH1A1 (0.45) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL30749308 | 0.88 | ALDH1A1 (0.45) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL30749295 | 0.80 | ALOX15 (0.39) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL27224063 | 0.80 | ALOX15 (0.39) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL27223533 | 0.79 | F2 (0.41) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL27223426 | 0.78 | KMT2A (0.47) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL30749239 | 0.78 | KMT2A (0.47) | ALDH1A1ALOX15MEN1KMT2ALMNA | |
| SCHEMBL30749254 | 0.77 | KMT2A (0.46) | ALDH1A1ALOX15MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573096-A1 | INHIBITORS OF MYELOPEROXIDASE | Astrazeneca AB (SE) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024038131-A1 | INHIBITORS OF MYELOPEROXIDASE | ASTRAZENECA AB (SE) | 2024-02-22 | — | — | WO | disclosed |